10 February 2010

New Associated Partner of P4L: IMTEK from the University of Freiburg

Today the Network for Biophotonics Photonics4Life welcomes a new associated Partner. The IMTEK, the Department of Microsystems Engineering from the University of Freiburg, will join P4L to add its expertise in active micro-optics. IMTEK develops tunable micro-lenses, micro-mirrors, and other micro-opto-mechanical components, which they assemble into complex optical microsystems, predominantly for use in medical applications. Especially the Laboratory for Micro-Optics with proficiency in optical design and modeling, fabrication and assembly technologies, and extensive capabilities in micro-optical characterization is established as one of the leading research groups in tunable micro-optics and micro-optics for medical diagnostics and is therefore ideally suited to complement the Network for Biophotonics.

Within Photonics4Life, IMTEK aims to conduct basic studies and developments for minimally invasive, extremely miniaturized endoscopic probes for biomedical applications. The probes will feature at least three functionalities as 3D shape sensing, imaging and 3D tomography. Special application fields are otology, especially ear implants and gastroenterology, in particular submucoase in small channels.

The IMTEK is one of about 100 departments of the University of Freiburg and is Europeʼs largest MEMS research department with 21 MEMS professors, more than 200 MEMS researchers and over 400 MEMS students. The department encompasses nearly all technical fields relevant to the highly interdisciplinary world of microsystems technology.

Laboratory for Micro-optics

The laboratory for micro-optics is one of the 20 different labs at IMTEK with a special focus on tunable optical components and devices for a wide field of applications. The research comprises design and simulation as well as technology developments, fabrication and characterization of single components, assembly and packaging up to prototyping including system metrology.

Head of the laboratory is Prof. Hans Zappe. The lab is divided into two groups: One group focuses on photonic crystals and electrowetting technology, PD Dr. Wolfgang Mönch is responsible for these topics. Dr. Andreas Seifert manages the other group with biomedical projects and developments for tunable micro-lenses and micro-mirrors. Currently 13 PhD students, additionally several diploma, bachelor and assistant students are involved in the research programs.

Main focus of current research topics

Endoscopic OCT:
Optical coherence tomography (OCT) is a non-invasive imaging technique allowing non-destructive imaging below the surface of tissue. We have developed an ultra-miniaturized OCT system suitable for use in an endoscope, to allow non-invasive medical diagnostics in, for example, the gastro-intestinal system or during keyhole surgery. Using two-dimensional scanning micro-mirrors and tunable micro-lenses, the 3 mm diameter system attains very high lateral resolution despite its compact dimensions.

Implantable oxygen sensor:
Continuous in vivo monitoring of blood oxygenation, pressure, and pulse, as well as the concentration of trace gasses in blood or perfusion in tissue, is of considerable clinical importance. We have developed a number of implantable micro-optical sensors for these measurements and demonstrated their utility and performance in experimental clinical trials. These biocompatible sensors measure numerous physiological parameters simultaneously, using techniques such as multi-wavelength absorption spectroscopy and new approaches for continuous blood pressure measurement.

Tunable photonic crystals:
Photonic crystals are novel periodic structures which exhibit an optical bandgap and are thus of considerable relevance for guiding and switching light in new-generation optical systems. We are advancing the capabilities of these devices by making photonic crystals tunable, using our competence in soft-matter micro-optics combined with new developments in optical polymers and novel actuation mechanisms.

Round Robin Experiment

Raman spectroscopy has already proved its effectiveness in many cases for medical diagnostics such as for cancer, cardiovascular diseases and infections. However, there are no standards in the different working groups, e.g. for sample preparation, implementation of the Raman experiments, spectra pre-treatment, data evaluation, etc.In a round robin experiment, the required groundwork will take place in order to define standardised Raman measurement methods, which will be fundamental for establishing Raman spectroscopy for clinical diagnostic procedures.

Latest News

5th International Conference on Biophotonics

20 March 2017

Continuing the success of the previous meetings held in Sacramento, Ottawa, Jena, and Florence, the 5th conference will come to Perth, Western Australia, running over two full days, and back-to-back with the Science on the Swan medical research conference, which delegates are strongly encouraged to also attend, at discounted rates. [more]

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