Department of Medicine 1, University Hospital Erlangen-Nuremberg

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Gastroenterology and Hepatology representing the central focus of the Department of Medicine 1 of the Erlangen University Clinic, have produced worldwide significant innovations and developments. From here, important impulses came from both the endoscopic diagnosis and treatment methods that are now standard procedure.

Using high resolution endoscopes all the major diseases of the oesophagus, stomach, pancreas, gut, as well as the hepatobiliary system can be efficiently assessed. In addition, the Department of Medicine 1 offers its experience in treatment of rare diseases (such as pseudodiverticulosis of the esophagus, eosinophilic gastroenteritis etc.).

Endoscopic procedures such as magnification endoscopy, chromoendoscopy, endomicroscopy, capsule endoscopy, intra-and extracorporal lithotripsy, single or double balloon endoscopy, inclusive various techniques for ESD or EMR, and many other procedures are also available at the Department of Medicine 1.

Highly experienced physicians and nurses will guarantee an optimal patient care and monitoring. Each step of the endoscopic treatment has been checked for accurate documentation. The extended medical experience and the interdisciplinary cooperation with surgery, ultrasound, radiology, and other institutions will be offered for complex cases.

Together with Erlangen Graduate School in Advanced Optical Technologies (Principal Investigator Dr.-Biophys. S.Douplik) Department of Medicine 1 is running two projects:

  1. Intrinsic Autofluorescence Endoscopy for diagnostics and surgerynavigation of stomach cancer. The main goal of the project is to decrease a high false positive rate and improve the specificity of the existing autofluorescence diagnostics. The main idea of the project is to extract an intrinsic autofluorescence image and thus reducecontribution of light absorption and scattering image peculiarities. The main technique proposed is based on image processing performing deconvolution and renormalization and rescaling of the conventional while light and autofluorescence images combinations.
  2. Video Endoscopy Hyperspectral and Fluorescence Imaging Diagnostics and Biopsy/Microsurgery Guidance for Stomach Cancer. The main goal is to create a videoendoscopy prototype to collect hyperspectral reflectance/fluorescence imaging dataset to diagnose early stages of cancer development. This project includes both hardware (optoelectronics) and software domains.

Address

Department of Medicine 1
University Hospital Erlangen-Nuremberg
Ulmenweg 18
91054 Erlangen

Germany

Website

http://www.medizin1.uk-erlangen.de/

Contact person

Prof.Dr.med. Markus Neurath

e-mail

Round Robin Experiment

Raman spectroscopy has already proved its effectiveness in many cases for medical diagnostics such as for cancer, cardiovascular diseases and infections. However, there are no standards in the different working groups, e.g. for sample preparation, implementation of the Raman experiments, spectra pre-treatment, data evaluation, etc.In a round robin experiment, the required groundwork will take place in order to define standardised Raman measurement methods, which will be fundamental for establishing Raman spectroscopy for clinical diagnostic procedures.

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